The application of anti-fatigue agent G-108(complex of m-phenylenediamine,cobalt salt and phenolic resin) in the tread underlayer compound of off-the-road tire was studied.The results show that,the heat build-up of the tread underlayer compound with anti-fatigue agent G-108 decreased significantly,self-adhesion property increased,vulcanization characteristics and physical properties changed little,and the endurance performance of the finished off-the-road tire increased.